Clarksdale, MO is assigned area code area code 816. Area code 816 is one of two original area codes assigned to Missouri and put into service on January 1, 1947.
In addition to Clarksdale, MO area code 816 serves west-central Missouri which includes the Kansas City metropolitian area and the larger cities and communities of Blue Springs, Gladstone, Grandview, Independence, Kansas City, Lee's Summit, Liberty, Kearny, Platte City, Raytown and St. Joseph, in addition to many smaller communities within the service area.
Clarksdale, MO is located in DeKalb County and observes the Central Time Zone.
View our Times by Area Code tool.